Further research is needed to validate the findings of this study and explore other aspects of HFREF patient management

Oct 13, 2025 by pynkocean.com 25 views

Relationship between the Degree of Left Ventricular Diastolic Dysfunction during Pre-discharge with Rehospitalization of 30 Days and 6 Months in Patients with Heart Failure with Reduced Ejection Fraction (HFREF) at H. Adam Malik Medan Hospital

Understanding Heart Failure with Reduced Ejection Fraction (HFREF)

Heart disease failure, also known as heart failure, is a complex medical condition that can result in changes in the structure and function of the heart. One of the main causes of heart failure is diastolic dysfunction and left ventricular systolic dysfunction (LV). This study aims to evaluate the relationship between the degrees of LV diastolic dysfunction before the patient is sent home and the risk of rehospitalization within 30 days and 6 months after returning home.

Background of the Study

Heart failure is a leading cause of morbidity and mortality worldwide, and its management is a significant challenge for healthcare providers. Diastolic dysfunction is a critical component of heart failure, and its assessment is essential for determining the severity of the condition. The degree of diastolic dysfunction can be classified into three grades: Grade I, Grade II, and Grade III. This study aims to investigate the relationship between the degree of LV diastolic dysfunction before discharge and the risk of rehospitalization within 30 days and 6 months after returning home.

Research Methodology

This study is a retrospective cohort study conducted on HFREF patients in the integrated heart center of H. Adam Malik Hospital Medan between January and December 2021. Echocardiography before repatriation is carried out to assess LV's diastolic dysfunction, and follow-up for rehospitalization is carried out through telephone calls 30 days and telephone calls 6 months after the return.

Research Result

From a total of 93 patients studied, it was found that 40 patients (43%) experienced diastolic dysfunction of LV Grade I, 22 patients (23.7%) grade II, and 31 patients (33.3%) grade III. A total of 34 patients (26.6%) experienced rehospitalization within 30 days after return, while 21 patients (26.6%) experienced rehospitalization within 6 months. The analysis shows a significant relationship between the degree of LV diastolic dysfunction before the return and rehospitization at 30 days after the return (p value 0,000), but not at 6 months after the return (p value 1,000).

Discussion

The results of this study indicate that the degree of LV diastolic dysfunction is more severe before the patient is discharged closely with an increased risk of rehospitalization in 30 days. This indicates the importance of a careful evaluation of the diastolic function of HFREF patients before returning. Patients with a higher degree of dysfunction may require more intensive medical attention and better management strategies to reduce the risk of complications.

However, the absence of a significant relationship with rehospitalization in 6 months shows that other factors can also play a role in the risk of long-term rehospitalization. This opens opportunities for further research to explore other aspects of HFREF patient management, such as treatment, compliance with therapy, and environmental factors that can affect patient health.

Conclusion

From this study, it can be concluded that the degree of LV diastolic dysfunction before returning in HFREF patients has a correlation with rehospitalization in 30 days. This discovery emphasizes the importance of proper monitoring and handling of diastolic conditions in patients with heart failure to improve their short-term results. Further research is needed to evaluate the factors that contribute to long-term rehospitalization and improve the quality of treatment for HFREF patients.

Implications of the Study

The findings of this study have significant implications for the management of HFREF patients. Proper evaluation and monitoring of diastolic function can help identify patients at high risk of rehospitalization. This can lead to the implementation of more intensive medical attention and better management strategies to reduce the risk of complications. Additionally, the study highlights the need for further research to explore other aspects of HFREF patient management, such as treatment, compliance with therapy, and environmental factors that can affect patient health.

Limitations of the Study

This study has several limitations that should be acknowledged. The study was conducted on a retrospective cohort of patients, which may limit the generalizability of the findings. Additionally, the study relied on echocardiography to assess diastolic function, which may not be the most accurate method. Further research is needed to validate the findings of this study and explore other aspects of HFREF patient management.

Future Directions

The findings of this study highlight the need for further research to explore other aspects of HFREF patient management. Future studies should investigate the relationship between diastolic function and other factors that contribute to rehospitalization, such as treatment, compliance with therapy, and environmental factors that can affect patient health. Additionally, studies should aim to develop more accurate and reliable methods for assessing diastolic function.
Q&A: Relationship between the Degree of Left Ventricular Diastolic Dysfunction during Pre-discharge with Rehospitalization of 30 Days and 6 Months in Patients with Heart Failure with Reduced Ejection Fraction (HFREF)

Q: What is the main objective of this study?

A: The main objective of this study is to evaluate the relationship between the degrees of left ventricular diastolic dysfunction before discharge and the risk of rehospitalization within 30 days and 6 months after returning home in patients with heart failure with reduced ejection fraction (HFREF).

Q: What is diastolic dysfunction, and how is it related to heart failure?

A: Diastolic dysfunction is a condition where the heart's ability to relax and fill with blood during diastole (the relaxation phase of the heart) is impaired. This can lead to an increase in pressure in the heart, which can cause the heart to work harder and eventually lead to heart failure.

Q: What are the different grades of diastolic dysfunction?

A: The different grades of diastolic dysfunction are:

Grade I: Mild diastolic dysfunction
Grade II: Moderate diastolic dysfunction
Grade III: Severe diastolic dysfunction

Q: What were the findings of this study?

A: The study found that there was a significant relationship between the degree of left ventricular diastolic dysfunction before discharge and the risk of rehospitalization within 30 days after returning home. However, there was no significant relationship between the degree of diastolic dysfunction and the risk of rehospitalization within 6 months after returning home.

Q: What are the implications of this study?

A: The findings of this study have significant implications for the management of HFREF patients. Proper evaluation and monitoring of diastolic function can help identify patients at high risk of rehospitalization. This can lead to the implementation of more intensive medical attention and better management strategies to reduce the risk of complications.

Q: What are the limitations of this study?

A: The study has several limitations, including:

The study was conducted on a retrospective cohort of patients, which may limit the generalizability of the findings.
The study relied on echocardiography to assess diastolic function, which may not be the most accurate method.
Further research is needed to validate the findings of this study and explore other aspects of HFREF patient management.

Q: What are the future directions for research?

A: Future studies should investigate the relationship between diastolic function and other factors that contribute to rehospitalization, such as treatment, compliance with therapy, and environmental factors that can affect patient health. Additionally, studies should aim to develop more accurate and reliable methods for assessing diastolic function.

Q: What can patients with HFREF do to reduce their risk of rehospitalization?

A: Patients with HFREF can reduce their risk of rehospitalization by:

Following their treatment plan and taking their medications as prescribed
Monitoring their symptoms and reporting any changes to their healthcare provider
Making healthy lifestyle choices, such as eating a balanced diet and exercising regularly
Attending follow-up appointments with their healthcare provider to monitor their condition and adjust their treatment plan as needed.

Q: What can healthcare providers do to reduce the risk of rehospitalization in patients with HFREF?

A: Healthcare providers can reduce the risk of rehospitalization in patients with HFREF by:

Conducting regular follow-up appointments to monitor the patient's condition and adjust their treatment plan as needed
Providing education and support to patients to help them manage their condition and reduce their risk of rehospitalization
Encouraging patients to follow their treatment plan and take their medications as prescribed
Monitoring patients for signs of worsening heart failure and adjusting their treatment plan accordingly.